Alobar holoprosencephaly: A case report

نویسندگان

  • Abdollahimohammad, Abdolghani Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
  • Amirshahi, Mehrbanu Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
  • Kerami, Azam Faculty of Medical Sciences Khomain, Arak University of Medical Sciences Arak, Iran
  • Mansoorifar, Leila Iran University of Medical Sciences, Tehran, Iran
  • Mirshekari, Fatemeh Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
  • Mirshekari, Leila Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
  • Mirshekari, Marzeeh Zahedan University of Medical Sciences, Zahedan, Iran
  • Naroei, Fereshteh Faculty of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran
  • Salehi, Ashraf Faculty of Medical Sciences Khomain, Arak University of Medical Sciences Arak, Iran
  • Sanagoo, Akram Nursing Research Center, Golestan University of Medical Sciences, Golestan, Iran
چکیده مقاله:

Holoprosencephaly (HPE) is a rare congenital brain malformation associated with multiple midline facial defects. This anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. HPE is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. In this study, we described a case of HPE in a neonate with gestational age of 32 weeks. Antenatal ultrasonographic diagnosis was performed, and the infant was presented with macrocephaly, bilateral microphthalmia, hypotelorism, proboscis and ambiguous genitalia.

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alobar holoprosencephaly: a case report

holoprosencephaly (hpe) is a rare congenital brain malformation associated with multiple midline facial defects. this anomaly is resulted from the failure of diverticulation and cleavage of primitive prosencephalon during weeks 4-8 of gestation. hpe is the most common forebrain developmental anomaly in human with the incidence rate of 0.49-1.2 cases per 10,000-20,000 term births. in this study,...

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Antenatal Sonographic Diagnosis of a Case of Alobar Holoprosencephaly: A Case Report

Holoprosencephaly is a rare congenital brain malformation resulting from failure of diverticulation and cleavage of primitive prosencephalon which occurs at 4th 8th week of gestation and is usually associated with multiple midline facial anomalies. Herein we report an antenatal case of such patient. Patient was evaluated and because of the magnitude of the problem induction was done which led t...

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Alobar holoprosencephaly: report of two cases with unusual findings.

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Antenatal Diagnosis of Alobar Holoprosencephaly

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Alobar holoprosencephaly associated with cebocephaly and craniosynostosis.

Cebocephaly is a very rare congenital midline facial anomaly characterized by a blind-ended single nostril and ocular hypotelorism, and is usually combined with alobar holoprosencephaly. We report here a case of alobar holoprosencephaly with cebocephaly and craniosynostosis. Chromosomal analysis revealed normal karyotyping. The facial dysmorphism was characterized by the single nostril, hypotel...

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عنوان ژورنال

دوره 2  شماره None

صفحات  70- 74

تاریخ انتشار 2015-11

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